BioGaia Osfortis - Probiotic Capsules
BioGaia is a world leader in probiotic research and development. Our clinically proven probiotics have been supporting the health and well-being of people everywhere, throughout every stage of life, since 1990.
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Why choose BioGaia's probiotics?
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Our clinically proven probiotics support your gut bacteria and overall health and wellbeing.
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We have spent over 30 years of research to develop probiotics for your body’s good bacteria.
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One daily dose of any of our products contains a minimum of 100 million live bacteria.
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BioGaia’s global research network
As a pioneer in the field, BioGaia has been at the forefront of probiotic and microbiome research for more than 30 years.
Our team of microbiologists, metabolism experts, process experts, and those responsible for clinical development collaborate with a comprehensive international network of leading researchers and doctors.
Research institutions and these partnerships allow us to validate our rationally designed probiotic formulations through rigorous clinical trials. Many of our trials are double-blind, randomized, and placebo-controlled, ensuring robust scientific evidence.
Over time, BioGaia has collaborated with numerousuniversities and hospitals worldwide for research studies. Clickto explore a selection of our research network.
- Swedish University of Agricultural Sciences, Uppsala, Sweden
- University of Gothenburg, Sweden l Örebro University, Sweden
- Texas Children’s Hospital, USA
- University hospitals in Bari and Turin, Italy
- Baylor College of Medicine, Houston, USA
- National University of Singapore
- University of Leuven, Belgium.
supporting the use for occasional constipation*
Guidelines for recommendation in Adults
Introducing L. reuteri: One of the world’s most studied probiotic
BioGaia’s products contain unique and patented strains of the lactic acid bacteria Limosilactobacillus reuteri, formerly known as Lactobacillus reuteri.
L. reuteri is a probiotic species whose natural habitat is the human body. Passed from generation to generation during childbirth and breastfeeding, L. reuteri has co-evolved with humans since the beginning of time.
Every product from BioGaia contains unique L. reuteri strains that provide their own distinct health benefits.*
Unfortunately, research shows that modern lifestyles have largely eradicated L. reuteri from the human microbiota in many people living a modern, Western lifestyle. By reintroducing L. reuteri through probiotic solutions, this crucial bacterial culture helps restore the potential of the human microbiome.*
Why recommend probiotic products with L. reuteri?
- L. reuteri is one of few bacterial species that has developed in symbiosis with humans. Due to this it naturally colonizes and has a strong adaptation.
- L. reuteri strains survive through the whole GI tract.
- BioGaia’s products with L. reuteri are manufactured under controlled conditions and of the highest quality and are 100 % safe to use.
- The number of live bacteria is guaranteed until expiry.
- Efficacy and safety are tested and documented in the target populations, from newborns to the elderly.
- Our probiotics contain viable freeze-dried L. reuteri .
- The probiotic bacteria are always defined on strain level.
L. reuteri reaches the gut alive
Probiotics originating from humans, like L. reuteri, possess a unique advantage as they have evolved alongside our physiology, potentially fostering a more symbiotic relationship with our gut microbiota.
This intimate co-evolution may enhance their ability to colonize effectively and exert targeted benefits within the human digestive system, making them particularly effective in promoting gut health*.
Live bacteria must survive the journey through the acidic environment of the stomach to reach the gut alive. Our clinical studies show that our carefully selected probiotic strains, such as L. reuteri, are proven to survive and reach the gut alive.
Limosilactobacillus reuteri
Stringent quality standards
From state-of-the-art manufacturing to storage and distribution, we follow strict guidelines. Our quality control measures ensure that every batch meets safety and efficacy standards.
Individually fermented and freeze-dried, the bacteria in our products remain dormant until they encounter saliva and reach a higher temperature, at which point they awaken, are clinically proven to be ‘alive’, and begin their probiotic effects.
Clinically proven safe for all ages
L. reuteri from BioGaia has been widely studied in clinical trials and has been shown to have probiotic, health-promoting effects in both children and adults.*
Numerous studies and meta-analyses have verified the safety of our L. reuteri strains for human consumption among individuals of all ages.
To be officially classifiedas probiotics according to WHO, probiotic products must contain live microorganisms that, when administered in adequate amounts, confer a health benefit on the host.
Collapsible content
1. Beneficial living microorganisms
1. Beneficial living microorganisms
The incredible diversity of microorganisms encompasses fungi, yeasts, viruses, and more, yet the most common probiotic microorganisms are bacteria.
To be called a probiotic, the bacteria must remain alive and maintain viability throughout the product’s shelf life. This requires expertise and careful handling during production, packaging, and storage. Exposure to humidity, high temperature, and the presence of oxygen all play a role; therefore, probiotics require meticulous end-to-end handling to ensure that these delicate microorganisms survive. BioGaia employs various methods to assess the viability and activity of our bacteria strains. These techniques ensure that all BioGaia probiotics remain alive, safe, and effective.
BioGaia is backed by science
We collaborate with leading academic research institutions and these partnerships allow us to validate our rationally designed probiotic formulations through rigorous clinical trials. Most of our trials are double-blind, randomized, and placebo-controlled, ensuring robust scientific evidence.
As of 2023, BioGaia probiotic strains have been tested in 266 clinical studies in 22 634 individuals. Read more about our strains and research here.
Stringent quality standards
From state-of-the-art manufacturing to storage and distribution, BioGaia follows strict international guidelines. Our quality control measures ensure that every batch meets safety and efficacy standards.
Individually fermented and freeze-dried, the bacteria in our products remain dormant until they encounter saliva and reach a higher temperature, at which point they awaken, are clinically proven to be ‘alive’, and begin their probiotic effects.
2. Dosage and “adequate amounts”
2. Dosage and “adequate amounts”
Probiotic supplement dosing is measured by Colony Forming Units or CFUs. Clinical trials with a specific probiotic strain determine how many CFUs are necessary to deliver the intended health benefit. If the product contains several different bacterial strains, each strain should be defined and contain the exact clinically relevant dose and clinical trials done on the exact same dosage.
“Adequate amounts” include the recommended CFUs at the end of shelf-life, not the date of manufacture. The natural decline of living bacteria during storage must be considered at the production stage.
All BioGaia probiotic products are tested for total viable count, and the bacteria count is confirmed at the end of shelf life.
Note, the number of strains is not the most important thing to look for in a probiotic supplement. It is more important to select a probiotic strain which has been tested for a specific indication
Reaches the GI tract alive
Live bacteria have to survive the journey through to acidic environment of the stomach if they are to reach the gut alive. Our clinical studies show that our carefully selected probiotic species, such as L. reuteri, are proven to reach the gut alive.
3. What are the health benefits of good bacteria?
3. What are the health benefits of good bacteria?
Bacteria and its role in human health.
It was not so long ago that all bacteria were thought to be bad. This was because the first bacteria we identified were pathogens that caused illnesses and infections. Today, we know that most bacteria are either completely harmless or even vital to our health.
BioGaia’s L. reuteri strains have shown notable effectiveness in over 250 clinical studies involving more than 22,000 individuals of various ages.
The future of health-boosting microorganisms
As science delves deeper and technology accelerates, the future of probiotics heralds exciting possibilities for shaping human health and well-being.*
This evolving landscape promises innovative solutions to address a myriad of health concerns, shaping the way we perceive and harness the power of beneficial bacteria for human well-being.*
In this exciting frontier, both traditional and next-generation probiotics are poised to elevate human health.*
Next-generation probiotics
Next-generation probiotics represent cutting-edge science in health and wellness. Empowered by new technologies, our researchers are unlocking the potential of these previously uncultivable powerhouses.
These advanced strains and formulations combine with precision science to target specific microbial imbalances, offering tailored solutions for diverse health concerns.
While research is still young, we believe the possibilities are vast. From our newly opened laboratory in Eslöv, Sweden, our industry-leading work in metagenomics and strain development contributes to the exciting field of next-generation probiotics.
Unlocking a new frontier for human health
Embracing a holistic approach to wellness, the future of probiotics – both traditional and next-generation probiotics – stand poised to revolutionize preventive healthcare, empowering healthcare providers and individuals to cultivate thriving microbial ecosystems and unlock their full potential for vitality and longevity.*
- Prebiotics are fibers that nourish beneficial bacteria.
- Probiotics are live microorganisms that offer health benefits when consumed in adequate amounts.
- Synbiotics combine both probiotics and prebiotics.
- Postbiotics are inactivated probiotics with potential health benefits.
Each type serves a distinct role in supporting overall well-being.
Prebiotics: Nourishing the microbiota
Prebiotics serve as nourishment for our microbiota. While humans cannot digest prebiotics, certain beneficial microbes can. These microbes produce beneficial compounds, such as short-chain fatty acids, through the utilization of prebiotics, thus promoting a healthy microbiota.
Ideally, a prebiotic should resist the actions of stomach acids, bile salts, and intestinal enzymes, remain unabsorbed in the upper gastrointestinal tract, and be easily fermentable by beneficial intestinal flora (Pandey et al., 2015).
Probiotics: Cultivating good bacteria
Probiotics are living microorganisms, often referred to as “good bacteria,” which can be sourced from various places including foods like yogurt or fermented foods, as well as probiotic supplements, such as BioGaia.
According to the World Health Organization and the Food and Agriculture Organization WHO/FAO, 2002, probiotics, when consumed in adequate amounts, confer health benefits on the host.
Postbiotics: Harnessing inanimate microorganisms
Defined by the International Scientific Association for Probiotics and Prebiotics (ISAPP) in 2021, postbiotics represent a novel approach to promoting health.
Postbiotics consist of inactive microorganisms and their byproducts, which confer health benefits on the host (Nat Rev Gastroenterol Hepatol, 2021).
This innovative category opens new avenues for supporting health with potential benefits complementing probiotics such as improved long-term shelf life stability in room temperature.